Longevity CEO street cred

i have spent way too long trying to get it to not have one of the dogs falling to their death ... kind of off brand for a dog longevity co

the perks of being a Dog CEO

you know it’s going to be a good uber ride when they open with “im not a conspiracy theorist, butttt…”

The bar for early-stage enterprise sales is much higher than many founders realize. I often get cold emails from founders asking for help—advice, airline intros etc. I want to help, and I do respond to great cold emails—but I am often disappointed at how little effort has been put in. It's common that founders haven't done their homework on me or on the person/company they're asking for an intro to. No, I am not going to forward a generic email to my most important customer, which links to a demo that doesn't apply to their use case and demonstrates zero homework to understand them, their business, and how your product helps. When I pursued Virgin during YC, I'd read Richard Branson's book. I'd studied the history of Virgin Atlantic. I knew what he cared about and what mattered to the airline. I showed up with a model of the Overture airplane beautifully painted in his favorite livery I loved our airplane model so much—it was the only one we had—that I didn't gift it to him. Fortunately, I realized this was dumb, went back, found his EA, and got her to hand deliver it to him. Had I not, probably there would be no Virgin deal during batch and Boom likely would have died long ago. It's a very noisy world out there—particularly with the explosion of AI drivel—and founders need to demonstrate that they've done an exceptional amount of homework when they reach out. End of rant.

Loyal’s mission has given us strong tailwinds (pun intended 😉)

i miss pre-2020 twitter it played a not-insignificant role in building my confidence & conviction to start Loyal. i learned SO much from the founders & investors who spent time sharing learnings + ideas here 2025 twitter is just plain demoralizing

Sitting here at day 2 of @LongevityDublin feeling uneasy with the presentation from TripleHelix about what they are doing with gene therapy outside of any regulation. Then the guy starts talking about SIRT1 gene therapy, and now I'm certain they don't know what they are doing. Then he starts talking about putting 9 different genes in combination into people based on complete guesses. This isn't science. It's not safe. It's irresponsible experimentation in humans. Glad at least one scientist here had the guts to stand up during Q&A and call it out for what it is. Thank you @ScheibyeKnudsen.

The Irish locals are advocating for Loyal species expansion (quite successfully)

tbh i may never again have an idea as good as loyal