NEW: In tea, onion & celery, the flavonoid apigenin inhibits the NAD-destroying enyzme CD38 & prevents muscle loss in obese rats by upping the anabolic enzyme p70S6K💪 Ozempic adjunct?💉🧵

Dose was 50 mg/kg in rats which is ~560 mg for a 70 kg /154 lb human

In 2013, with Euardo Chini's lab, my student at the time, Nathan Price, did a HTS screen & discovered apigenin and quercetin as CD38 inhibitors that can raise NAD levels in vivo and improve glucose and lipid metabolism in obese mice 🐀